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Sildenafil is a powerful and selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5), which is accountable for degradation of cGMP while in the corpus cavernosum. The molecular structure of sildenafil is comparable to that of cGMP and acts to be a aggressive binding agent of PDE5 inside the corpus cavernosum, resulting in extra cGMP an
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